At 56 (turning 57 in February 2026), Jennifer Aniston continues to turn heads with her impossibly radiant, youthful complexion. The Friends legend’s secret? A controversial treatment dubbed the “salmon sperm facial” – yes, you read that right!

Aniston first confessed to trying it in a 2023 WSJ. Magazine interview, laughing about her aesthetician’s suggestion: “Are you serious? How do you get salmon’s sperm?” Despite the initial shock, she gave it a go, later joking on Jimmy Kimmel Live! in 2024, “Don’t I have beautiful salmon skin?” While she admitted uncertainty about dramatic results, her flawless glow speaks volumes.
The treatment isn’t literal fish semen – it’s purified DNA fragments called polynucleotides (PDRN) extracted from salmon or trout sperm cells. Injected via microneedling or directly, these molecules mimic human DNA closely, stimulating collagen production, boosting hydration, reducing inflammation, and aiding skin regeneration for that coveted “glass skin” effect.
Originating in South Korea over a decade ago (brands like Rejuran), it’s exploded globally. Aniston isn’t alone: Kim Kardashian raved about injecting “salmon sperm into my face” on The Kardashians (2024), while Denise Richards credited Jen for inspiring her, and stars like Charli XCX, Miley Cyrus, and Khloé Kardashian have followed suit. As of 2025, reports from The Hollywood Reporter and dermatologists confirm it’s a top Hollywood anti-aging trend.
Science offers backing: Studies in journals like Pharmaceuticals (2021) and Journal of Dermatological Treatment (2024) show PDRN improves elasticity, heals damage, and enhances texture. Though not FDA-approved for injections in the US (often off-label or topical), celebs swear by the natural, regenerative glow without fillers’ frozen look.
Jen pairs it with weekly peptide injections, lasers, facials, and healthy living. Recent 2025-2026 photos show her skin smoother and brighter than ever – plump, poreless perfection.
Gross name, stunning results. Would you inject salmon sperm for Aniston-level radiance?
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