Hollywood’s eternal youth icon, Jennifer Aniston, has everyone talking about her most outrageous beauty hack yet – the infamous “salmon sperm facial”! At 56, the Friends star continues to defy age with glowing, plump skin, and her secret weapon? Injecting DNA derived from salmon sperm directly into her face.
Aniston first spilled the beans in a 2023 interview with WSJ. Magazine, admitting her aesthetician recommended the treatment. “First of all, I said, ‘Are you serious? How do you get salmon’s sperm?'” she recalled with a laugh. Despite her initial shock, Jen went ahead with it – though she later joked on Jimmy Kimmel Live! in 2024, “Don’t I have beautiful salmon skin?” while admitting she wasn’t sure it made a huge difference.
But the trend has exploded since then, with A-listers like Kim Kardashian (who got it injected on The Kardashians), Charli XCX, and Denise Richards jumping on board. Known scientifically as polynucleotides or PDRN (polydeoxyribonucleotide), it’s not raw sperm slathered on – it’s purified DNA fragments extracted from salmon or trout sperm cells. These molecules are injected via microneedling to stimulate collagen production, boost hydration, reduce inflammation, and promote skin regeneration.
Originating in South Korea (where it’s been popular for over a decade under brands like Rejuran), the treatment promises dewy “glass skin,” fewer fine lines, improved elasticity, and faster healing. Studies back some claims: Research in journals like Pharmaceuticals (2021) and Journal of Dermatological Treatment (2024) show PDRN accelerates wound healing, enhances collagen, and improves texture.
At 56 (turning 57 in February 2026), Aniston looks radiant as ever, crediting a mix of facials, lasers, peptides, and healthy living – but this fishy facial adds that extra “shock” factor. No FDA approval for injections in the US yet, so it’s often topical or off-label, but celebs swear by the glow.
Would you try salmon sperm for eternal youth? Jen’s flawless complexion might just convince you – gross name, gorgeous results!
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